Five years after the initial changes, the world is drastically different to how it used to be.
After the shift, Jeff, the original user of the Chronivac was now the pet of rather eccentric Dalmatian named Elise , who used to be Jeff's pet. Elise ended up in possession of the Chronivac after Jeff but didn't realise what it was and sold it off on an auction site.
As it moved from owner to owner, the users each did something both worldwide and personal. Some other drastic changes to the world included:
Cows no longer existing in the world.
Humans being used as dairy animals and milk producers.
Dogs having 8 foot tails
Female dogs being able to develop breasts like human females.
Cats being a sentient race that is at war with dogs.
And various other changes.
As for Jeff, in the past 5 years many things have happened to the boy. A few days after the shift, Elise got him neutered as she didn't want a Jeff to be a breeder.
As for the other things that Elise put Jeff through, a lot of it included dressing him up. Like humans used to do with dogs before the shift, many dogs will put accessories on humans. Elise will often dress Jeff up in a skirt and pink shirt that give the impression of femininity despite Jeff being clearly Male.
Jeff can't think to car however as he lacks any higher brain function to complain about the clothing. He just shakes his butt and pants complacently.