Your body liquefies, to the point that you lie on the floor in a literal puddle at first. Then, suddenly, your cells reassemble themselves. It is the single strangest sensation you've ever experienced, and when you fully re-form, it's gotten weirder. You have become an anthropomorphic vixen. You stare at your brand-new hand-paw-things in utter shock, as do all the other transformed students.
Then some of them start to move. A large German shepherd dog-man approaches and takes hold of your wrist, pulling you up.
"Matt. I saw you change. It's me, Alice, your, um... girlfriend? Not really sure anymore." He smiles, but you detect that there is something more behind that smile than friendly good will. You gently try to remove your arm from his grip, but he holds on. Yeah, something's up. He is a large male, you're a small female, this might not end well.
"Alice, please let go of me. I think the chemicals went to your head." Your newly-feminine voice takes you by surprise, but you mentally approve of the calming, level-headed sound of it, even if you don't want to keep it. Alice keeps his grip on you.
"No... I feel great, actually. Boy, these male hormones are... powerful, and you're quite pretty," he says as he pulls you in closer, grinning even wider. Your eyes widen in fear as your suspicions of his intentions are confirmed, but as a former male, you know their critical weakness.
"Alice, it's time we broke up." You bring your knee up as hard as possible into Alice's newly-male crotch. The new you might be small and feminine, but you're also pretty athletic, apparently. Alice doesn't even make a noise, sliding to the ground in pain. Glancing around, you see similar scenes. About a fifth of the victims of the chemicals clearly got overwhelmed by the chems or hormones. Putting the thought of others less fortunate out of your head, you book it out of the gym as quickly as possible. As you dash through the chaotic hallways, you mentally note various aspects of your new body. You're definitely quite athletic, as you rocket down the halls. You have a better sense of balance, too, which your rather fluffy tail probably helps. Your senses are superior in every way, and you note with some confusion that you've suddenly become noticeably more agile. It probably has to do with the fact that you've lost about a foot of height and overall just turned much smaller. While you're overall faster, you notice several cat-girls with the same idea as you, who are practically doing gymnastics on their way out. You thank your lucky stars that your girlfriend-turned-would-be-rapist didn't get turned into a fox or horse.
As you arrive in the parking lot, you see a ton of police barricades. They were clearly prepared for this outcome - mostly. Instead of screeching to a halt like most of the other escaping students do, you and a few of the faster species run full tilt at the barricades, either bowling the bewildered officers over, or, in the case of the cats, nimbly dodging amongst them and tripping them. A tranquilizer dart just barely misses you, and you and a cat-girl take cover behind your car.
"If you can't get to your car, ride with me," you tell her. She nods, and switches her claws in and out nervously. You unlock the door, and the two of you slide in and floor it. You look up towards Heaven and silently mutter thanks that your home is out in the country, where they'll have a hard time getting to you. You turn to your new friend.
"I'm Matthew Jackson... I guess. I don't think they gave us new names, not like I waited around to check. What's yours?" you ask. The cat's face visible brightens.
"Matt! It's me, Brandon!" It's your turn to light up. Brandon is your best friend - you've done all kinds of crazy crap together.
"Well, I guess I don't have to prepare you for my home!" you say, laughing. Then all the humor drains away as your situation hits home with full force. Brandon senses the change in attitude.
"Yeah. We just had our lives... I would say wrecked, more like surgically removed... with our parents' permission."